GSA, ESICM, and SCCM Issue Joint Statement Highlighting Links Between COVID-19 and Sepsis
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Today a consensus paper by ESICM, SCCM, and the GSA was published in Intensive Care Medicine, emphasizing the importance of recognizing that patients critically ill with COVID-19 have viral sepsis, despite some differences from sepsis caused by other pathogens.

“Sepsis should become a widely used umbrella term for a condition that is caused by different pathogens, including SARS-CoV-2”, says Tex Kissoon, GSA President.  “This pandemic has shown us the effectiveness of international and horizontal cooperation between healthcare professionals and policymakers. We must keep the focus on infection prevention measures and use the successful trial platforms set up during the pandemic to support research on sepsis. Above all governments should integrate sepsis in the national health systems, as urged by the WHA resolution of 2017“, concludes Kissoon.

The three organizations also warn that patients who survive other forms of sepsis suffer longer-term ill-effects similar to those of patients with “long-COVID”, although they are not equally well recognized. Scientific literature demonstrates that longer-term effects of sepsis, known as post-sepsis syndrome, occur in up to 50% of sepsis survivors, who suffer from persisting physical, cognitive, and psychological sequelae.


What Is Sepsis?

Sepsis arises when the body’s response to an infection injures its own tissues and organs. It may lead to shock, multi-organ failure, and death – especially if not recognized early and treated promptly. Sepsis is the final common pathway to death from most infectious diseases worldwide, including viral infections such as SARS-CoV-2 / COVID-19.

The following video explains sepsis in 3 minutes - including the most common causes, symptoms, how it can be diagnosed and treated, and more.

Simone Mancini
World Sepsis Congress 2021 – Session 14 and 15 Now Available on YouTube and as a Podcast

Sessions 14 and 15 from the World Sepsis Congress 2021 are now available on YouTube (embedded above) and as a Podcast on Apple Podcasts (just search for World Sepsis Congress in your favorite podcast app).


Session 14 was chaired by our very own Luis Antonio Gorordo Del Sol and features the following participants:

  • Why and How the Phenotype Matters – Chris Seymour, University of Pittsburgh, USA

  • Janus Kinase Inhibition in Severe COVID-19 – Andre Kalil, University of Nebraska, USA

  • Anti C5a in Severe COVID-19 and Sepsis – Diederik van de Beek, University of Amsterdam, The Netherlands

  • Anti-Complement Therapy Against COVID-19 – Courtney Campbell, The Ohio State University Wexner Medical Center, USA

  • Biomarker Guided Immunomodulatory Therapy in COVID-19 – Evangelos Giamarellos, European Sepsis Alliance, Greece

  • Biomarkers for the Assessment of ADM Targeted Treatments – Peter Pickkers, Radboud University Medical Center, The Netherlands


Session 15 was moderated by Maha Aljuaid, Member of the GSA Executive, and features the following presentations:

  • Surviving Sepsis Campaign and Efforts to Incorporate Input From LMICs – Laura Evans, University of Washington, USA

  • The Role of the WHO in Developing the COVID-19 Living Guideline – Janet Diaz, World Health Organization, Switzerland

  • Cardiovascular Management in Children in Sepsis Depends on Context – Suchitra Ranjit, Apollo Hospitals, India

  • Fluid Resuscitation in Adults: Different Settings, Different Strategies? – Shevin Jacob, African Research Collaboration on Sepsis, Uganda

  • Antibiotics in the First Hour: For Everyone Everywhere? – Fernando Zampieri, Hospital for the Heart, Brazil

  • The ARCS Delphi Study on Quality Indicators for Sepsis in LMICs – Emmanuel Nsutebu, African Sepsis Alliance, United Arab Emirates


This concludes World Sepsis Congress 2021 - all sessions and talks are now available to rewatch on YouTube and Apple Podcasts. Thanks for your interest and support over the last weeks. World Sepsis Congress will return in 2022.


World Sepsis Congress 2021 is a project by the Global Sepsis Alliance, initiator of World Sepsis Day and World Sepsis Congress.

Marvin Zick
Sepsis-Forum by the German Sepsis Foundation – Free and Online on June 22, 2021
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Our friends from the German Sepsis Foundation (Sepsis-Stiftung) are hosting their first annual Sepsis-Forum next week, on June 22, 2021 - and you are invited!

Over the course of 4.5 hours, 2 sessions, 2 panel debates, and a Q&A session, experts from the health sector and sepsis survivors will discuss long-term consequences of sepsis and COVID-19 as well as the challenges for affected individuals, the scientific community, and the health care system itself.

The event is entirely virtual, free of charge, and in German. A short registration on the event website is required.

Marvin Zick
WSC 2021 Report: Statistics and Numbers from the World Sepsis Congress 2021

Thank you so much for participating in the World Sepsis Congress 2021. It was a tremendous success, thanks to you.

We had 19,230 registrations from 181 countries, which is very inspiring. Even more important to us is that 71 % of our audience joined from low- and middle-income countries - many of those would have never been able to afford to travel to a physical congress, let alone COVID making this impossible anyway. This truly emphasizes our mission with World Sepsis Congress – to bring knowledge about sepsis to all parts of the world.

We are also thrilled with your feedback - it was off the charts! You can click through the full report above and download it as a PDF below. Feel free to share this report with interested colleagues or friends.

Session 1 through 13 of the WSC 2021 are already available on YouTube and as a Podcast on Apple Podcasts, with sessions 14 and 15 being released tomorrow. Thanks for your interest over the last weeks – World Sepsis Congress will return in April 2022.

Marvin Zick
Pediatric Sepsis Data Colaboratory – Colab-Orate With Us in the Fight Against Sepsis
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The Pediatric Sepsis Data CoLaboratory (Sepsis Colab) is a new international data-sharing network of healthcare workers, policymakers, researchers, and advocacy partners collaborating to address the high burden of pediatric sepsis mortality and morbidity globally. The network was formed through a partnership between the Centre for International Child Health (CICH) at BC Children’s Hospital in Vancouver and the World Federation of Pediatric Intensive and Critical Care Societies (WFPICCS).

The vision for the Sepsis CoLab arose out of the recognition that despite important milestones recently achieved in the fight against sepsis, lack of routinely collected data and coordination is hampering progress. The Sepsis CoLab shares data to further common priorities among collaborators to improve sepsis treatments and outcomes and facilitates partnerships to develop and validate tools for data collection and sharing, enabling continuous quality improvement of care in health facilities across the world.

Those interested in joining the Sepsis CoLab are invited to complete a brief Membership Application here.

Sepsis CoLab Members are provided with networking opportunities and mentorship as well as access to a host of resources shared through Scholars Portal Dataverse, a secure, open-source data repository.

Marvin Zick
World Sepsis Congress 2021 – Session 12 and 13 Now Available on YouTube and as a Podcast

Sessions 12 and 13 from the World Sepsis Congress 2021 are now available on YouTube (embedded above) and as a Podcast on Apple Podcasts (just search for World Sepsis Congress in your favorite podcast app).


Session 12 was chaired by Farhad Imam from the Bill & Melinda Gates Foundation and features the following participants:

  • Improving Yield and Time to Results of Blood Cultures – Evgeny A. Idelevich, University Hospital Greifswald, Germany

  • The Role of Point of Care Pathogen Identification to Fight Overuse of Antibiotics – Holger Rohde, University Hospital Hamburg, Germany

  • Metagenomics for Pathogen Detection and Pandemic Response – Senjuti Saha, Child Health Research Foundation, Bangladesh

  • Scaling Pathogen Detection for Sepsis in the Global Health Setting – Jessica Manning, International Center of Research, Cambodia

  • The Challenges of AMR in Fighting Tuberculosis – Martin Grobusch, University of Amsterdam, The Netherlands

  • Sepsis and AMR: Therapeutic and Diagnostic Innovations – Where Are We? – Taslimarif Saiyed, Centre for Cellular and Molecular Platforms, India


Session 13 was moderated by Louise Thwaites from the Oxford University Clinical Research Unit in Vietnam and features the following presentations:

  • Evidence for Role of Biomarkers for Antibiotic Stewardship – Philipp Schütz, Aarau Cantonal Hospital, Switzerland

  • How Precision Medicine Will Change Sepsis Management – Tom van der Poll, University of Amsterdam, The Netherlands

  • mRNA Signatures of Sepsis and Insights Into Causative Organisms – Purvesh Khatri, Stanford University, USA

  • Theragnostics and Phenotyping for the Enrichment of Sepsis Trials – Where Are We? – Hector Wong, Cincinnati Children‘s Hospital, USA

  • Revival of Robust Manual Solutions for Sepsis Diagnostic and AMR Surveillance in Low-Resource Settings: Case Study of Médecins Sans Frontières Mini-Lab – Jean-Baptiste Ronat, Doctors Without Borders, France

  • Harnessing Digital Technologies for Sepsis Diagnosis and Decision Support – Alison Holmes, Imperial College London, UK


Sessions are released weekly on Tuesdays. The next and final sessions will be ‘Immunomodulatory Treatments in Sepsis and Severe COVID-19 ‘ and ‘Global Standards and Guidelines for the Management of Sepsis and COVID-19 Patients’ on June 15th, 2021.


World Sepsis Congress 2021 is a project by the Global Sepsis Alliance, initiator of World Sepsis Day and World Sepsis Congress.

Marvin Zick
Sepsis Tech & Innovation 2021 – Two-Day Virtual Conference on June 22-23, 2021
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Our friends from the Sepsis Alliance are hosting ‘Sepsis Tech & Innovation 2021’, a two-day virtual conference on June 22-23, 2021.

This conference brings sepsis technology development together with clinical leadership to connect ideas, products, and implementation to improve patient care across the continuum of care, from sepsis prevention, diagnostics, therapeutics, rehabilitation, and recovery. Highly respected nationally renowned speakers will explore various aspects of technology developments in clinical practice, innovation, investment, and policy that will impact the future of sepsis care.

We strongly suggest you take a look at the program and sign up for free for this amazing online event!

Marvin Zick