2nd WSC - Antimicrobial Therapy and Source Control II Now Available

Session 7 of the 2nd World Sepsis Congress ‘Antimicrobial Therapy and Source Control II’ is now available to view on YouTube (embedded above) and as a Podcast on Apple Podcasts (iTunes link).
It is chaired by Satish Bhagwanjee from the US and features the following presentations and speakers:

  • Role of Procalcitonin for Antibiotic Stewardship – Beat Müller

  • Indication and Choice of Antifungals – Thierry Calandra

  • Challenges to Implementation of Antibiotic Stewardship – Alison Holmes

  • Tackling Antimicrobial Resistance in Enterobacteriaceae – Ana Gales

  • Empirical Antimicrobial Therapy in Times of AMR – David Paterson

  • Beta Lactams – Better by Continuous Infusion? – Jeffrey Lipman

Sessions are released weekly on Thursdays. The next session is ‘Evidence Based Treatment of Sepsis I’ on November 8th, 2018. Please head over to the 2nd WSC website for the full release schedule.The 2nd WSC is brought to you free of charge by the Global Sepsis Alliance, fostering our aspiration to bring knowledge about sepsis to all parts of the world. If you enjoyed it, please consider making a donation.

Marvin Zick
Presentations from WSD Supporter Meeting at ESICM LIVES 2018 in Paris
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On October 23rd, World Sepsis Day Supporters from all over the world came together at ESICM LIVES 2018 in Paris for a World Sepsis Day Supporter Meeting.

Konrad Reinhart, Chair of the Global Sepsis Alliance, Kubilay Demirag, Chair of the Turkish Society of Intensive Care, Maha Aljuaid, GSA Advance Speaker, and Marvin Zick, General Manager of the GSA, gave presentations, which you can view and download below. Imrana Malik, GSA Advance Coordinator, could not be there in person, but her slides are available below as well.

Additionally, WSD Supporters from all over the world reported on their activities and plans, and we discussed how we can jointly eradicate sepsis to make our vision “A World Free of Sepsis” a reality.


Summary of This Year’s GSA and WSD Activities - MArvin Zick


Strategy of the GSA to Implement WHO Sepsis Resolution - Konrad Reinhart


The Exemplary Success of the WSD Campaign in Turkey - Kubilay Demirag


GSA Advance - Imrana Malik


Progress of the National Sepsis Plan in Saudi Arabia - Maha Aljuaid


Our next World Sepsis Day Supporter Meeting will take place at ISICEM Brussels in March 2019. The exact date and location will be announced on our website early 2019 as well as send out via our newsletter. A form to sign up will be available here.

Marvin Zick
2nd WSC - Importance of Pathogen Detection and Sepsis Markers Now Available

The sixth session of the 2nd World Sepsis Congress ‘Importance of Pathogen Detection and Sepsis Markers’ is now available to view on YouTube (embedded above) and as a Podcast on Apple Podcasts (iTunes link).
It is chaired by Steven Opal from the US and features the following presentations and speakers:

  • How to Improve Yield and Time to Results of Blood Cultures – Peter Keller

  • Understanding Abnormal Coagulation Tests in Sepsis – Beverley Hunt

  • Novel Approaches to Faster Detection of Antibiotic Resistance – Marin Kollef

  • Procalcitonin for Infection Management in the ICU – Evelien de Jong

  • Transcriptional Diagnostics in Sepsis – Tom van der Poll

  • Precision Medicine Will Change Sepsis Management – Michael Bauer

Sessions are released weekly on Thursdays. The next session is ‘Antimicrobial Therapy and Source Control II’ on November 1st, 2018. Please head over to the 2nd WSC website for the full release schedule.

The 2nd WSC is brought to you free of charge by the Global Sepsis Alliance, fostering our aspiration to bring knowledge about sepsis to all parts of the world. If you enjoyed it, please consider making a donation.

Marvin Zick
Paul Allen’s Cause of Death Revealed to Be Septic Shock, a Known Complication of Non-Hodgkin Lymphoma
By Miles Harris [CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)], from Wikimedia Commons

By Miles Harris [CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)], from Wikimedia Commons

On October 15th, 2018, Paul Allen, co-founder of Microsoft, passed away at the age of 65 at the Swedish Medical Center in Seattle, Washington. While his cause of death was originally reported as “complications” of Non-Hodgkin Lymphoma, newly available documents (via TMZ) reveal his immediate cause of death was septic shock, resulting from underlying lymphoma-associated immunosuppression.

This is a profoundly sad outcome, but by no means a surprising one. There is a strong and undeniable relationship between cancer, its detrimental effects on the immune system, and the subsequent development of infections that lead to sepsis and septic shock. Cancer of all types increases the risk of developing sepsis by 10-fold(1). In addition, cancer patients have a 55% higher chance of dying from sepsis than noncancer patients(2).

The immune system of a cancer patient can be markedly suppressed by the cancer itself or by medications used to treat the cancer. This leads to a reduced ability to fight deadly bugs, as well as common organisms found throughout our environment, which generally do not pose a threat to healthy individuals. As a result, infections lead to sepsis which is often the final common pathway to death for cancer patients.

Sepsis remains one of the most underestimated (and under-reported) health threats worldwide, affecting 27 to 32 million people annually, of which 7 to 9 million die. Sepsis affects both rich and poor alike, although the burden is heavily weighted to the poor. However, early recognition and treatment can save many lives.

 

About Sepsis

Sepsis arises when the body’s response to an infection injures its own tissues and organs. Sepsis is an emergency; it may lead to shock, multiple organ failure, and death, especially if not recognized early and treated promptly. Sepsis is most common in people with compromised immune systems, like the very young, the very old, and those with chronic diseases like AIDS, cancer, diabetes, or Parkinson’s disease. But people can also develop sepsis from a simple scrape, wound, or burn injury. Septic shock is the most severe end of the spectrum. Organs begin to shut down and, unchecked, multi‐organ failure and death can ensue. Many patients who survive suffer from long-term disabilities.

 

About Paul Allen

Paul Allen was an American business magnate, philanthropist, and investor. He is best known for founding Microsoft with Bill Gates in 1975. He was estimated to be one of the wealthiest persons in the world, with an estimated net worth of $21.7 billion. He had a multibillion-dollar investment portfolio, including technology, real estate holdings, media companies, scientific research, and more. He founded the Allen Institute for Brain Science, the Institute for Artificial Intelligence, and Stratolaunch Systems. Over the course of his life, Allen gave more than $2 billion to education and arts, wildlife and environmental conservation, community services, healthcare, and more.

 

About the Global Sepsis Alliance and the World Sepsis Day Movement

The Global Sepsis Alliance (GSA) is a non-profit charity organization with the mission to provide global leadership to reduce the worldwide burden of sepsis. The GSA is initiator of World Sepsis Day on September 13th every year and World Sepsis Congress, a series of free online congresses bringing knowledge about sepsis to all parts of the world.

 

Press Release

A press release and contact persons for interviews are available.

 

Learn More About Sepsis

 

References

1. Martin et al. N Engl J Med; 348:1546 –1554; 2003.
2. Danai PA et al. CritCare Med 129:1432-1440;2006.

Marvin Zick
2nd WSC Report: Statistics and Numbers from the 2nd World Sepsis Congress
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Thank you so much for participating in the 2nd World Sepsis Congress. It was a huge success, thanks to you.

We had 20,000 registrations from more than 166 countries, which is simply amazing. Even more important to us is that 57 % of our audience joined from low- and middle-income countries - many of those would have never been able to afford to travel to a physical congress. This truly emphasizes our mission with World Sepsis Congress - to bring knowledge about sepsis to all parts of the world.

We are also very happy with your feedback - both the overall congress, the speakers, and the content were very much liked by you. You can see the full report embedded below and download it as a PDF. Feel free to share this report with interested colleagues or friends.

 
 

As you know, the 2nd World Sepsis Congress featured 103 renowned experts from 29 countries who gave 10-minute presentations on all aspects of sepsis over the course of 17 sessions and two days. Everything took place online and was completely free of charge, enabling everybody everywhere to participate and learn about sepsis, the most preventable cause of death worldwide. The sessions of the congress are released to YouTube and Apple Podcasts on Thursdays. Please visit the congress website for the full release schedule.

 

The 3rd World Sepsis Congress is planned for Fall 2020. For 2019, we will be hosting another World Sepsis Congress Spotlight, a smaller satellite congress shining a spotlight on one particular aspect of sepsis. Make sure to sign the World Sepsis Declaration and up to our newsletter to be informed once more information is available.

Marvin Zick
2nd WSC - Improving Early Detection and Quality of Care Now Available

The fifth session of the 2nd World Sepsis Congress ‘Improving Early Detection and Quality of Care’ is now available to view on YouTube (embedded above) and as a Podcast on Apple Podcasts (iTunes link).
It is chaired by Vida Hamilton from Ireland and features the following presentations and speakers:

  • Inequalities in Sepsis Treatment Around the World – Flavia Machado

  • Every Hour Counts – Lessons from New York State – Christopher Seymour

  • The Key Role of Emergency Medicine – Luis Garcia-Castrillo Riesgo

  • Nurses Hold the Key to Quality Sepsis Care – Ruth Kleinpell

  • Limitations of qSOFA for Early Detection – Flavia Machado

  • Automated Sepsis Alerts and Rapid Response Teams – Edgar Jimenez

  • Lactate for Detection and Management of Sepsis – Charles Sprung

Sessions are released weekly on Thursdays. The next session is ‘Importance of Pathogen Detection and Sepsis Markers’ on October 25th, 2018. Please head over to the 2nd WSC website for the full release schedule.

The 2nd WSC is brought to you free of charge by the Global Sepsis Alliance, fostering our aspiration to bring knowledge about sepsis to all parts of the world. If you enjoyed it, please consider making a donation.

Marvin Zick
Reminder: Submit Your Picture for 2018 WSD Event Poster
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Thank you so much for participating in World Sepsis Day last month - you hosted countless events all over the world to raise awareness for sepsis, the most preventable cause of death worldwide.

Like in the previous years, we will summarize all events on the 2018 WSD Event Poster - please submit your event now to be featured on the poster - submissions will close on October 31st, 2018.

Important: Please point your colleagues and friends to our website to submit their event - www.worldsepsisday.org/wsdposter

Please note that you can only upload one picture per event, so make sure to choose the best/the most representative one.

Since the poster will eventually be printed, we require a certain picture quality. If the form gives you an error message that the picture is too small, please make sure you get the original file off the camera or smartphone, without compressing it. Please don’t submit pictures you have received through WhatsApp, as it compresses pictures beyond recognition.

Please use only the provided form to submit your events - we can’t use pictures that are emailed to us or sent through social media. If you have trouble accessing the form, please try a different browser, a different device, a different network, or get in touch.

We plan to complete the poster by late November/early December, and we will make it available for download, as well as sent out printed copies, which you will be able to ‘order’ free of charge as soon as the poster is completed.

Please point your colleagues and friends to our website to submit their events, especially if you know that they did an event for World Sepsis Day.

Marvin Zick
2nd WSC - Epidemiology of Sepsis Now Available

The fourth session of the 2nd World Sepsis Congress ‘Epidemiology of Sepsis’ is now available to view on YouTube (embedded above) and as a Podcast on Apple Podcasts (iTunes link).
It is chaired by Jeremy Kahn from the US and features the following presentations and speakers:

  • National Estimates for China – Bin Du

  • Global and National Estimates Using ICD Data – Carolin Fleischmann-Struzek

  • Mapping Disease in Resource-Limited Settings – Rahsan Haniffa

  • National Estimates Using Electronic Heath Records – Chanu Rhee

  • National Estimates for Sweden Based on Chart Review – Adam Linder

  • Challenges to Assess the Global Burden of Sepsis – Kristina Rudd

Sessions are released weekly on Thursdays. The next session is ‘Improving Early Detection and Quality of Care’ on October 18th, 2018. Please head over to the 2nd WSC website for the full release schedule.

The 2nd WSC is brought to you free of charge by the Global Sepsis Alliance, fostering our aspiration to bring knowledge about sepsis to all parts of the world. If you enjoyed it, please consider making a donation.

Marvin Zick